Thermo Fisher Scientific PHGDH Monoclonal Antibody (05)

Applications

ELISA (ELISA)

• Tested Dilution: 1:1,000–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PGDH/PHGDH.

Target Information

The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is essential for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene have been associated with congenital microcephaly, psychomotor retardation, and other symptoms.
Multiple alternatively spliced transcript variants have been identified, though the full-length nature of most is not known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.