Thermo Fisher Scientific PRDX6 Recombinant Rabbit Monoclonal Antibody (1A9W5)
PRDX6 단백질을 인식하는 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, Protein A로 정제되었습니다. 인간, 마우스, 랫트 시료에 반응하며, 연구용으로만 사용 가능합니다.
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- MA555518
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1A9W5 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 125–224 of human Peroxiredoxin 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
KGMPVTARVV FVFGPDKKLK LSILYPATTG RNFDEILRVV ISLQLTAEKR VATPVDWKDG DSVMVLPTIP EEEAKKLFPK GVFTKELPSG KKYLRYTPQP
Target Information
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are associated with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins) share amino acid sequence homology, contain active site cysteine residues, and exhibit thiol-specific antioxidant activity across all kingdoms.
Mammalian Prx includes six members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx. Except for Prx VI, which belongs to the 1-Cys subgroup, the other five 2-Cys Prx isotypes exhibit thioredoxin-dependent peroxidase (TPx) activity using thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kDa in size and vary in subcellular localization: Prx I, II, and VI in cytosol; Prx III in mitochondria; Prx IV in ER and secretion; and Prx V distributed in peroxisome, mitochondria, and cytosol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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