Thermo Fisher Scientific IMPACT Polyclonal Antibody, MaxPab
IMPACT 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 및 랫트 시료에 반응합니다. Western blot에 적합하며, 높은 특이성과 순도를 가진 액상 형태 제품입니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
- 카탈로그번호
- H00055364-B01P
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IMPACT Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB)
Tested Dilution
- 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IMPACT (AAH34016, 1–320 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAEGDAGSDQ RQNEEIEAMA AIYGEEWCVI DDCAKIFCIR ISDDIDDPKW TLCLQVMLPN EYPGTAPPIY QLNAPWLKGQ ERADLSNSLE EIYIQNIGES ILYLWVEKIR DVLIQKSQMT EPGPDVKKKT EEEDVECEDD LILACQPESS VKALDFDISE TRTEVEVEEL PPIDHGIPIT DRRSTFQAHL APVVCPKQVK MVLSKLYENK KIASATHNIY AYRIYCEDKQ TFLQDCEDDG ETAAGGRLLH LMEILNVKNV MVVVSRWYGG ILLGPDRFKH INNCARNILV EKNYTNSPEE SSKALGKNKK VRKDKKRNEH
Target Information
Translational regulator that ensures constant high levels of translation upon various stress conditions such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment, and glucose deprivation. Acts as a negative regulator of EIF2AK4/GCN2 kinase activity, impairing GCN1-mediated activation and subsequent eIF-2-alpha phosphorylation, thereby preventing down-regulation of protein synthesis. Plays a role in neuronal differentiation by stimulating neurite outgrowth through inhibition of EIF2AK4/GCN2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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