ELK Biotechnology PDGFR-α (phospho Tyr762) rabbit pAb
PDGFR-α (phospho Tyr762) rabbit polyclonal antibody로, 인산화된 PDGFR-α를 검출하는 데 사용됩니다. IHC, IF, ELISA에 적합하며, 세포막 및 골지체에 위치한 단백질 연구에 활용됩니다. 인간, 마우스, 랫트 시료에 반응합니다.
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PDGFR-α (phospho Tyr762) Rabbit Polyclonal Antibody
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | PDGFR-α (phospho Tyr762) rabbit pAb |
| Alternative Names | PDGFRA; PDGFR2; RHEPDGFRA; Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD14 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PDGFR alpha around the phosphorylation site of Tyr762 (AA range: 731–780) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 5156 |
| Human Swiss-Prot No. | P16234 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Cell projection (cilium); Golgi apparatus |
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor (PDGF) family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR-α and PDGFR-β polypeptides.
Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and various other cancers.
[Provided by RefSeq, Mar 2012]
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