
ELK Biotechnology PDGFR-α (phospho Tyr762) rabbit pAb
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Product name: | PDGFR-α (phospho Tyr762) rabbit pAb |
Alternative Names: | PDGFRA; PDGFR2; RHEPDGFRA; Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD14 |
Applications: | IHC;IF;ELISA |
Recommended Dilutions: | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human PDGFR alpha around the phosphorylation site of Tyr762. AA range:731-780 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
GeneID(Human): | 5156 |
Human Swiss-Prot No: | P16234 |
Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cell projection, cilium . Golgi apparatus . |
Background: | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012], |
Species Reactivity: | Human;Mouse;Rat |
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