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ELK Biotechnology PDGF-B rabbit pAb
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ELK Biotechnology PDGF-B rabbit pAb

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PDGF-B rabbit pAb는 인간, 생쥐, 랫드 시료에서 PDGFB 단백질을 검출하기 위한 폴리클로날 항체입니다. IF, WB, IHC, ELISA에 적합하며, 고순도 IgG 형태로 제공됩니다. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성을 제공합니다.

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ELK Biotechnology ES6530-100UL PDGF-B rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES6530-50UL PDGF-B rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology PDGF-B rabbit pAb

PDGF-B rabbit pAb

제품 정보

항목 내용
Product name PDGF-B rabbit pAb
Alternative Names PDGFB; PDGF2; SIS; Platelet-derived growth factor subunit B; PDGF subunit B; PDGF-2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-Sis; Becaplermin
Applications IF; WB; IHC; ELISA
Recommended Dilutions IF: 1:50–200
WB: 1:500–1:2000
IHC: 1:100–1:300
ELISA: 1:10000
Not yet tested in other applications.
Immunogen The antiserum was produced against synthesized peptide derived from human PDGFB. AA range: 16–65
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 27 kDa
GeneID (Human) 5155
Human Swiss-Prot No. P01127
Cellular localization Secreted. Released by platelets upon wounding.
Species Reactivity Human; Mouse; Rat

Background

Platelet derived growth factor subunit B (PDGFB) is a member of the PDGF/VEGF protein family. The encoded preproprotein undergoes proteolytic processing to produce PDGF subunit B, which can form homodimers or heterodimers with PDGF subunit A. These dimers bind and activate PDGF receptor tyrosine kinases, influencing various developmental processes. Mutations in PDGFB are linked to meningioma, and chromosomal translocations involving this gene are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing leads to multiple transcript variants.

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