ELK Biotechnology Rho H rabbit pAb
Rho H 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 세포 성장 조절 연구 및 혈액암 관련 연구에 적합. -20°C에서 1년 보관 가능.
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ELK Biotechnology Rho H rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Rho H rabbit pAb |
| Alternative Names | RHOH; ARHH; TTF; Rho-related GTP-binding protein RhoH; GTP-binding protein TTF; Translocation three four protein |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RhoH (AA range: 141-190) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 21 kD |
| Gene ID (Human) | 399 |
| Human Swiss-Prot No | Q15669 |
| Cellular Localization | Cytoplasm; Cell membrane; Lipid-anchor; Cytoplasmic side. Colocalizes with ZAP70 in the immunological synapse. |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. It is expressed in hematopoietic cells, functioning as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin’s lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5′ untranslated region results in multiple transcript variants that encode the same protein. (RefSeq, May 2013)
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