Thermo Fisher Scientific eIF2 gamma Polyclonal Antibody
eIF2 gamma 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합. Human과 Mouse 시료에 반응하며, 고순도의 Affinity chromatography 정제 제품. 단백질 합성 개시 인자 연구용으로 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF2S3 (Accession P41091), corresponding to amino acid residues A86–P136 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850008 |
Product Specific Information
This antibody detects endogenous levels of total EIF2G/EIF2S3.
Target Information
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex consists of three subunits—eIF2 alpha, eIF2 beta, and eIF2 gamma—that form a ternary complex with GTP and tRNA during early translation initiation.
eIF2S3 (eukaryotic translation initiation factor 2, subunit 3), also known as eIF2G, is a 472 amino acid protein belonging to the gamma subfamily of GTP-binding elongation factor proteins. It forms a heterotrimer with alpha and beta chains, binding ribosomal subunits and catalyzing preinitiation complex formation essential for protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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