Thermo Fisher Scientific FOS Monoclonal Antibody (OTI1F12), TrueMAB
인간 FOS 단백질을 인식하는 단클론 항체로 Western blot 및 IHC(P) 응용에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도의 액상 형태로 제공됩니다. PBS/BSA/glycerol 완충액에 보관하며 -20°C에서 보존합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F12 |
| Immunogen | Full length human recombinant protein of human FOS produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates genes involved in signal transduction, cell proliferation, and differentiation.
Phosphorylation of c-Fos occurs at multiple sites in response to stimuli such as growth factors and insulin. The ERK MAPK kinase phosphorylates Threonine 232, influencing nuclear localization and transcriptional activity of c-Fos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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