Thermo Fisher Scientific KCTD11 Polyclonal Antibody
Rabbit polyclonal antibody targeting human KCTD11, validated for Western blot. Synthetic N-terminal peptide immunogen (aa 61-110). High purity via Protein A, 1 mg/mL in PBS with sucrose and sodium azide. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human KCTD11 (aa 61–110) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607319 |
Product Specific Information
- Peptide sequence: ADFYQIRPLL DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH
- Sequence homology: Human: 100%; Mouse: 90%
Target Information
Calponin, a thin filament-associated protein, is involved in the regulation and modulation of smooth muscle contraction. It binds actin, calmodulin, troponin C, and tropomyosin. Calponin is expressed in smooth muscle and tissues rich in smooth muscle.
Two isoforms exist: 34 kDa and 29 kDa. The 29 kDa isoform is mainly expressed in urogenital tract muscle. Calponin expression is also seen in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes, and nerve fibers.
Calponin helps identify myoepithelial cells in breast lesions and differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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