Thermo Fisher Scientific NKX2-5 Monoclonal Antibody (3C1)
인간 NKX2-5 단백질을 인식하는 마우스 단클론 항체로 심장 발달 관련 연구에 적합. Western blot, ICC/IF, ELISA, IP 등 다양한 응용 가능. PBS(pH 7.4) 버퍼에 보존되며, -20°C에서 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 15 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C1 |
| Immunogen | NKX2-5 (NP_004378, 1 a.a. – approximately 130 a.a.) full-length recombinant protein with GST tag. MW of GST tag alone is 26 kDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MFPSPALTPT PFSVKDILNL EQQQRSLAAA GELSARLEAT LAPSSCMLAA FKPEAYAGPE AAAPGLPELR AELGRAPSPA KCASAFPAAP AFYPRAYSDP DPAKDPRAEK KELCALQKAV ELEKTEADNA *
Target Information
This gene encodes a homeobox-containing transcription factor that functions in heart formation and development.
Mutations in this gene are associated with:
- Atrial septal defect with atrioventricular conduction defect
- Tetralogy of Fallot (heart malformation disease)
- Congenital hypothyroidism non-goitrous type 5 (non-autoimmune condition)
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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