Thermo Fisher Scientific Carbonic Anhydrase XI Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:40-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic protein corresponding to residues near the C terminal of human Carbonic Anhydrase XI. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carbonic Anhydrase XI,uniProtId:O75493-1,ncbiNodeId:9606,antigenRange:328,antigenLength:328,antigenImageFileName:PA5-68371_Carbonic_Anhydrase_XI_O75493-1_Rabbit.svg,antigenImageFileNamePDP:PA5-68371_Carbonic_Anhydrase_XI_O75493-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.1 mg/mL

Purification

affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2688537

Target Information

Carbonic Anhydrase XI (CA11, CA XI) is a member of the carbonic anhydrases (CAs) family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic Anhydrase XI participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Further, Carbonic Anhydrase XI show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.