Thermo Fisher Scientific Venezuelan Equine Encephalitis Virus NSP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Venezuelan equine encephalitis virus (strain Trinidad donkey) (VEEV) Non-structural polyprotein (27-167aa)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.912 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% Proclin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_3090406

Target Information

Venezuelan equine encephalitis virus (VEEV) is a member of genus Alphavirus in the family Togaviridae|VEEV encodes four nonstructural proteins (nsP1, nsP2, nsP3 and nsP4) and five structural proteins (capsid (C), envelope (E) 3, E2, 6k, and E1)|The Nsp1 gene of VEEV contains a 51-nt conserved sequence element (CSE) that is essential for virus replication|Mutation or deletion of CSE results in loss of infectivity of VEEV, probably due to inefficient recognition of the viral RNA core promoter element by the virus replication complex|Nsp1 functions as a methyltransferase and guanylylation enzyme, two properties needed for the 5` capping of VEEV genomic RNA [PMID: 30781656]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.