Thermo Fisher Scientific TSSC4 Polyclonal Antibody
TSSC4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에서 검증됨. Human 시료에 반응하며, 합성 펩타이드 면역원으로 제작. PBS와 2% sucrose buffer에 보관되며, -20°C에서 보존. 종양 억제 관련 연구용으로 적합.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TSSC4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690563 |
Product Specific Information
This target displays homology in the following species:
- Human: 100%
Target Information
TSSC4 is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and various cancers such as lung, ovarian, and breast cancer.
This gene is located among several imprinted genes; however, both this gene and the pan-hematopoietic expression gene (PHEMX) escape imprinting. TSSC4 may play a role in malignancies and diseases involving this region. Several transcript variants encoding two different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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