Thermo Fisher Scientific WDR92 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human WDR92. Recombinant protein control fragment (Product #RP-96034). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:WDR92,uniProtId:Q96MX6-1,ncbiNodeId:9606,antigenRange:176-248,antigenLength:357,antigenImageFileName:PA5-57235_WDR92_Q96MX6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57235_WDR92_Q96MX6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649630

Product Specific Information

Immunogen sequence: YNQEERVVCA GYDNGDIKLF DLRNMALRWE TNIKNGVCSL EFDRKDISMN KLVATSLEGK FHVFDMRTQH PTK

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-a and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.