Thermo Fisher Scientific MFSD2B Polyclonal Antibody
Human MFSD2B 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 세포 내 약물 수송 관련 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MFSD2B. Recombinant protein control fragment (Product # RP-99710) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term); for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2643923 |
Product Specific Information
- Immunogen sequence: VGSTPKTPSR DASSRLSLRR RTSYSL
- Antigen sequence identity: Mouse – 77%, Rat – 85%
Target Information
Multidrug transporters such as MFSD2B are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Members of the Major Facilitator Superfamily (MFS) transport various substrates including sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, though most are substrate-specific.
MFSD2B is closely related to MFSD2A, which is highly expressed in liver and brown adipose tissue (BAT) during fasting. Unlike MFSD2A, MFSD2B is expressed in fewer tissues at lower levels and is not induced during fasting, suggesting distinct physiological roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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