Thermo Fisher Scientific LZTR1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human LZTR1 for IHC (paraffin) applications. Recognizes recombinant LZTR1 protein. Supplied as liquid at 0.1 mg/mL. For research use only; not for diagnostic or resale purposes.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LZTR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643654 |
Product Specific Information
Immunogen sequence:
HSCSDSVEYL TLNFGPFETV HRWRRLPPCD EFVGARRSKH TVVAYKDAIY VFGGDNGKTM LNDLLRFDVK DCSWCRAFTT GTP
Highest antigen sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family. The encoded protein localizes exclusively to the Golgi network, where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental defect involving the third and fourth pharyngeal pouches, leading to absence of thymus and parathyroid glands, congenital cardiac abnormalities, and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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