Thermo Fisher Scientific FOLH1 Monoclonal Antibody (OTI3H5), TrueMAB
FOLH1(PSMA) 단백질을 인식하는 단클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H5 |
| Immunogen | Full length human recombinant FOLH1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different substrates, including folate and N-acetyl-L-aspartyl-L-glutamate. It is expressed in tissues such as the prostate, central and peripheral nervous system, and kidney. Mutations may impair folate absorption, leading to low blood folate levels and hyperhomocysteinemia. Expression in the brain may relate to glutamate excitotoxicity, and in the prostate, it is up-regulated in cancer cells, serving as a diagnostic and prognostic marker for prostate cancer. Alternative splicing generates multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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