Thermo Fisher Scientific TIA1 Monoclonal Antibody (OTI1D7), TrueMAB
TIA1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(Paraffin)에서 검증됨. HEK293T 세포에서 생산된 full-length human recombinant protein을 면역원으로 사용. Affinity chromatography로 정제되었으며, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D7 |
| Immunogen | Full length human recombinant protein of human TIA1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from:
- WNT protein (WNT3A) to stabilize beta-catenin
- Noggin, which is a bone morphogenetic protein inhibitor
Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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