Thermo Fisher Scientific MTF2 Polyclonal Antibody
MTF2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 비결합형 액상 포맷, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MTF2. Recombinant protein control fragment (Product #RP-105464) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665242 |
Product Specific Information
Immunogen sequence:
AHLCLYNLSVI HKKKYFDSEL ELMTYINENW DRLHPGELAD TPKSERYEHV LEALNDYKTM FMSGKEI
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 99%
Target Information
Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at Lys-36 (H3K36me3) and recruits the PRC2 complex.
Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex, enhancing PRC2 H3K27me3 methylation activity.
Regulates transcriptional networks during embryonic stem cell self-renewal and differentiation.
Promotes PRC2 complex recruitment to inactive X chromosome and Hox gene repression.
May also inhibit PRC2 activity by activating CDKN2A gene and promoting cellular senescence.
Binds to the metal-regulating-element (MRE) of MT1A gene promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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