Thermo Fisher Scientific ASIC1 Polyclonal Antibody
ASIC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, IP 등 다양한 실험에 사용 가능. Lyophilized 형태로 제공되며 -20°C에 보관. 고순도 0.8 mg/mL 농도, ASIC1 연구용으로 최적화된 항체.
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Thermo Fisher Scientific ASIC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide CQKEAKRSSADKGVALSLDD, corresponding to amino acid residues 469–488 of rat ASIC1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735484 |
Product Specific Information
- Shipped at room temperature as a lyophilized powder.
- Store at -20°C upon receipt.
- Reconstitution: add 50 µL of deionized water.
Target Information
ASIC1 belongs to the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. These are amiloride-sensitive sodium channels with intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop rich in cysteine residues.
ASIC1 is expressed in most brain neurons and may function as an ion channel subunit. It is a cation channel gated by extracellular protons and inhibited by amiloride, permeable to Ca²⁺, Li⁺, and K⁺.
Expression is observed in dorsal root ganglia, sciatic nerves, olfactory bulb, cortical regions, hippocampus, amygdala, cerebellum, and other brain regions. Isoform 3 is expressed only in dorsal root ganglion, while isoform 1 is expressed in DRG, spinal cord, and trigeminal ganglia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-77730_ASIC1_P55926-1_Rabbit.svg, PA5-77730_ASIC1_P55926-1_Rabbit_PDP.jpeg)
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