Thermo Fisher Scientific ICOSLG Monoclonal Antibody (OTI2G10), TrueMAB
ICOSLG 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot 및 IHC(Paraffin)에서 검증됨. 인간 시료에 반응하며, 1 mg/mL 농도의 액상형 항체. Affinity Chromatography로 정제되었으며 PBS/BSA/Glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G10 |
| Immunogen | Full length human recombinant protein of human ICOSLG produced in HEK293T cell (Target: CD275 (B7-H2), UniProt ID: O75144-1, Antigen Range: 1–302) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family regulating T-cell activation and function.
ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli in peripheral tissue.
Binding to ICOSL delivers a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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