Thermo Fisher Scientific Human PD-L1 (B7-H1) Fc Chimera Recombinant Protein
PD-L1(B7-H1) Fc 키메라 재조합 단백질로, HEK293 세포에서 발현된 비결합형 단백질입니다. WB, IHC, ELISA 등 다양한 면역학적 분석에 사용 가능하며, 종양 면역 회피 연구에 활용됩니다. 동결건조 형태로 -20°C 이하에서 안정적으로 보관됩니다.
- 카테고리
- Protein
- 판매단위
- pk
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- ELISA: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Expression System | HEK293 cells |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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