Thermo Fisher Scientific USP20 Polyclonal Antibody
Human 및 비인간 영장류에 반응하는 Rabbit Polyclonal Antibody. IHC(P)에서 10 µg/mL로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC(P)]: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from internal region of human USP20 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550561 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
- Human, Gorilla, Monkey, Marmoset (100%)
- Orangutan, Gibbon, Rabbit (94%)
- Hamster (89%)
- Mouse, Bovine, Bat, Elephant, Panda, Horse, Pig, Opossum, Turkey, Chicken (83%)
- For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
SLAIN2 is closely related to SLAIN1, a novel stem cell protein expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to regulate microtubule (MT) growth and organization.
SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG.
Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in MT regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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