Thermo Fisher Scientific DCK Polyclonal Antibody
DCK 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC, IP 등 다양한 응용에 적합. 고순도 액상 형태로 제공되며 1.0 mg/mL 농도. 세포 내 DCK 발현 연구 및 약물 반응성 분석에 활용 가능.
- 카탈로그번호
- PA521846
- 판매단위
- pk
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Thermo Fisher Scientific DCK Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:10,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment containing amino acids 1–260 (P27707) of DCK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11152040 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, A549, mouse brain, PC-12, Rat2
- Predicted reactivity: Mouse (93%), Rat (92%), Chicken (82%), Rhesus Monkey (96%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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