Thermo Fisher Scientific GRSF1 Polyclonal Antibody
Human GRSF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용되며, 4°C 또는 -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GRSF1. Recombinant protein control fragment (Product #RP-102758). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642226 |
Product Specific Information
- Immunogen sequence:
YSQESKTTYL EDLPPPPEYE LAPSKLEEEV DDVFLIRAQG LPWSCTMEDV LNFFSDCRIR NGEN - Highest antigen sequence identity to orthologs:
- Mouse: 89%
- Rat: 88%
Target Information
G-rich sequence factor 1 (GRSF1) is a regulator of post-transcriptional mitochondrial gene expression. It is required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. GRSF1 binds RNAs containing the 14-base G-rich element and preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA — ND6 mRNA and the long non-coding RNAs for MT-CYB and MT-NDS — each of which contains multiple consensus binding sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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