Thermo Fisher Scientific GLRA1 Monoclonal Antibody (7F8E2)
GLRA1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료 반응성이 있으며 Protein G로 정제된 액상 형태입니다. GLRA1 관련 신경계 연구 및 질환 모델 분석에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7F8E2 |
| Immunogen | Purified recombinant fragment of human GLRA1 (AA: 29–154) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787363 |
Product Specific Information
MA5-31740 has been tested in indirect ELISA.
Target Information
GLRA1 is a subunit of a pentameric inhibitory glycine receptor that mediates postsynaptic inhibition in the central nervous system.
Defects in GLRA1 cause startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome.
Multiple transcript variants encoding different isoforms have been found for GLRA1.
Glycine receptors (GlyR) including GLRA1 are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of glycine.
GLRA1 is widely distributed throughout the CNS, particularly within the hippocampus, spinal cord, and brain stem.
Diseases associated with GLRA1 include Hyperekplexia, Hereditary 1 and Hyperekplexia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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