Thermo Fisher Scientific APOB48R Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human APOB48R. Recombinant protein control fragment (Product #RP-98786). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:APOB48R,uniProtId:Q0VD83-4,ncbiNodeId:9606,antigenRange:686-785,antigenLength:1097,antigenImageFileName:PA5-59864_APOB48R_Q0VD83-4_Rabbit.svg,antigenImageFileNamePDP:PA5-59864_APOB48R_Q0VD83-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638081

Product Specific Information

Immunogen sequence: AGCGTEEGEA SVSENQELDG STGADAGPCP SLGEAYARET EDEEAEADRT SRRGWRLQAV AVGLPDREDA QTGSVAAGIM GGDVVPHISA AGAGEALEGV

Highest antigen sequence identity to the following orthologs: Mouse - 36%, Rat - 36%.

Target Information

Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.