Thermo Fisher Scientific CD36 Polyclonal Antibody
CD36 단백질을 인식하는 Thermo Fisher Scientific의 기니피그 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 생쥐, 원숭이, 랫드 반응성이 있으며, 동결 건조 형태로 제공되어 장기 보관이 용이합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Guinea pig / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from extracellular domain of human CD36 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CD36.
Target Information
CD36, also known as scavenger receptor class B member 3, is a protein expressed on the surface of various cell types, including macrophages, platelets, and adipocytes. It plays a role in lipid metabolism, inflammation, and atherosclerosis, and is involved in the recognition and uptake of ligands such as oxidized low-density lipoproteins, long-chain fatty acids, and apoptotic cells.
CD36 is implicated in malaria pathogenesis, acting as a receptor for thrombospondin in platelets and other cells. It is the fourth major glycoprotein on platelet surfaces and binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been identified.
Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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