Thermo Fisher Scientific GNA11 Polyclonal Antibody
Thermo Fisher Scientific의 GNA11 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 토끼 유래 다클론 항체입니다. Western blot에 최적화되어 있으며, 합성 펩타이드를 면역원으로 사용했습니다. 액상 형태로 0.5 mg/mL 농도이며, PBS(2% sucrose) 용액에 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human GNA11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690088 |
Product Specific Information
This target displays homology in the following species:
Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
Target Information
Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. Over 20 known Gα subunits are classified into four families — Gα(s), Gα(i/o), Gα(q), and Gα(12) — based on structural and functional similarities. Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, as substitution of phenylalanine for Tyr356 alters receptor interaction and abolishes ligand-induced IP3 formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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