Thermo Fisher Scientific DARPP-32 Monoclonal Antibody (2G6D9)
DARPP-32 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, Flow cytometry, ELISA에 사용 가능. Human 시료 반응성. 단백질 G 정제, PBS 버퍼, 0.05% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific DARPP-32 Monoclonal Antibody (2G6D9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G6D9 |
| Immunogen | Purified recombinant fragment of human PPP1R1B (aa 95–204) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898519 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
DARPP-32 is a dopamine (DA) and AMP-regulated ~32 kDa phosphoprotein associated with dopaminoceptive neurons.
When phosphorylated on Thr34, DARPP-32 inhibits Protein Phosphatase I. When phosphorylated on Thr75, it acts as an inhibitor of PKA.
Phosphorylation of DARPP-32 plays a critical role in the regulation of dopaminergic neurotransmission and is also implicated in the actions of alcohol, caffeine, and Prozac®.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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