Thermo Fisher Scientific MRPL49 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence:
  ESVDEYQFVE RLLPATRIPD PPKHEHYPTP SGWQPPRDPP PNLPYFVRRS

• Sequence homology:
  Cow: 86%
  Dog: 86%
  Guinea Pig: 92%
  Horse: 92%
  Human: 100%
  Mouse: 79%
  Rabbit: 83%
  Rat: 86%

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition, in contrast to prokaryotic ribosomes where this ratio is reversed. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary greatly among species, making sequence homology recognition difficult. This gene encodes a 39S subunit protein and shares some 3' UTR sequences with the HRD1 gene. Pseudogenes corresponding to this gene are located on chromosomes 5q and 8p.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.