Thermo Fisher Scientific BBS9 Polyclonal Antibody
BBS9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 사용 가능. 인간 및 생쥐 반응성. 액상 형태이며, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PA5100220
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: [참고 문헌 없음]
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BBS9 (Accession Q3SYG4), corresponding to amino acid residues G767–D817 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815750 |
Product Specific Information
Antibody detects endogenous levels of total BBS9.
Target Information
The BBSome complex functions as a coat complex required for sorting of specific membrane proteins to the primary cilia. It is essential for ciliogenesis but dispensable for centriolar satellite function. This process involves Rab8 GDP/GTP exchange factor, which localizes to the basal body and interacts with the BBSome. Rab8(GTP) promotes extension of the ciliary membrane by facilitating vesicle docking and fusion at the ciliary base. Proper BBSome complex assembly and localization are required for this function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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