Thermo Fisher Scientific RAD54B Polyclonal Antibody
RAD54B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 인간 RAD54B 중간 영역 합성 펩타이드로 면역화. 높은 종간 상동성과 안정적인 액상 형태로 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human RAD54B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2576292 |
Product Specific Information
Peptide sequence:
NSLKPLSMSQ LKQWKHFSGD HLNLTDPFLE RITENVSFIF QNITTQATGT
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%
Target Information
The RAD54B protein belongs to the DEAD-like helicase superfamily and shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, which are involved in homologous recombination and DNA repair. It binds to double-stranded DNA and exhibits ATPase activity in the presence of DNA. RAD54B is highly expressed in testis and spleen, indicating active roles in meiotic and mitotic recombination. Homozygous mutations have been observed in primary lymphoma and colon cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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