Thermo Fisher Scientific GRK7 Monoclonal Antibody (1C11)
Human GRK7 단백질에 특이적인 Mouse 모노클로날 항체로 ELISA에 적합합니다. 비결합형 액상 형태이며 -20°C에서 보관합니다. 단백질 키나아제 신호전달 연구 및 시각 관련 단백질 분석에 활용됩니다.
- 판매단위
- pk
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1C11 |
| Immunogen | GRK7 (NP_631948, 1–100 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MVDMGALDNL IANTAYLQAR KPSDCDSKEL QRRRRSLALP GLQGCAELRQ KLSLNFHSLC EQQPIGRRLF RDFLATVPTF RKAATFLEDV QNWELAEEGP
Target Information
GRK7 is a serine/threonine kinase specifically expressed in the retina. It phosphorylates cone opsins and initiates their deactivation. Protein kinases mediate signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products and is classified into 8 major groups based on catalytic domain sequences. Tyrosine kinases (TK) regulate cell-cell interactions such as differentiation, adhesion, motility, and death. There are ~90 TK genes, including receptor TKs (EGFR, EPH, FGFR, PDGFR, TRK, VEGFR) and cytosolic TKs (ABL, FAK, JAK, SRC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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