
Thermo Fisher Scientific Apolipoprotein D/APO-D Monoclonal Antibody (APOD/3413)
인간 Apolipoprotein D(APOD)을 인식하는 마우스 단클론 항체로, IHC(P), Peptide Array, Immunoelectrophoresis에 사용 가능. 200 µg/mL 농도의 액상 형태로 제공되며, 단백질 A/G로 정제됨. 인간 간, 신장, 비장을 양성 대조군으로 사용 가능.
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Thermo Fisher Scientific Apolipoprotein D/APO-D Monoclonal Antibody (APOD/3413)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
| Immunoelectrophoresis (IE) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | APOD/3413 |
| Immunogen | Human recombinant APOD protein fragment (around aa21–119) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is stable for 24 months.
- Positive Control: Human liver, kidney, or spleen.
- Cellular Localization: Secreted.
- Specificity Comments:
Lipids such as phospholipids, triacylglycerols, and cholesterol are weakly soluble in aqueous solution and transported as components of lipoproteins. Lipoproteins consist of a non-polar core surrounded by phospholipid, cholesterol, and apolipoproteins. Apolipoprotein D (apoD) is part of the lipocalin superfamily, binding small hydrophobic molecules like arachidonic acid (AA). Its ability to bind AA suggests involvement in membrane phospholipid signal transduction and metabolism. ApoD expression correlates with cell cycle arrest and prognosis in several malignancies, including astrocytomas and medulloblastomas.
Target Information
Apolipoprotein D (APOD) is a component of high-density lipoprotein (HDL) with no marked similarity to other apolipoproteins. It shares homology with plasma retinol-binding protein and alpha-2 microglobulin superfamily members (lipocalins). This glycoprotein is closely associated with lecithin:cholesterol acyltransferase, an enzyme involved in lipoprotein metabolism.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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