Thermo Fisher Scientific Acrosomal Vesicle Protein Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:20–1:50

Product Specifications

Product Specific Information

Immunogen sequence:
SGEHASGEQA SGAPISSTST GTILNCYTCA YMNDQGKCLR GEGTCITQNS QQCMLKKIFE GGKLQFMVQG CENMCPSMNL FSH

• Highest antigen sequence identity to orthologs:
  • Mouse: 71%
  • Rat: 72%

Target Information

This gene encodes a testis-specific differentiation antigen, Acrosomal Vesicle Protein 1, which arises within the acrosomal vesicle during spermatogenesis. It is associated with the acrosomal membranes and matrix of mature sperm.
The gene consists of four exons, and alternative splicing generates multiple distinct transcripts encoding protein isoforms ranging from 81 to 265 amino acids.

Transcript abundance distribution:

• Longest transcript: 53–72%
• Second largest: 15–32%
• Third: 3.4–8.3%
• Fourth: 8.7–12.5%
• Remaining transcripts: <1%

The protein may be involved in sperm-zona binding or penetration and is a potential contraceptive vaccine immunogen for humans.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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