Thermo Fisher Scientific ANKRD32 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ANKRD32. Recombinant protein control fragment (Product #RP-96854). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ANKRD32,uniProtId:Q9BQI6-1,ncbiNodeId:9606,antigenRange:354-445,antigenLength:1058,antigenImageFileName:PA5-59301_ANKRD32_Q9BQI6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59301_ANKRD32_Q9BQI6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637978

Product Specific Information

Immunogen sequence: EYAKESKAMA IKTDVDVVEI KNTLRKHIYR AQAVRYNCIR IDKQPVYNVE VKNAEFPRGV LNLIESLIEG HFFKEAIEEL STLQAHYIPP VC

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.

Target Information

Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.