Thermo Fisher Scientific NOTCH1/activated Notch1 Polyclonal Antibody
NOTCH1/activated Notch1 폴리클로날 항체로, 인간, 마우스, 랫트 시료에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고순도 항체입니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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- BS-11976R
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human NOTCH1/activated Notch1 (amino acids 1651–1750) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in the extracellular region. In mammals, four Notch genes (Notch1, Notch2, Notch3, Notch4/Int-3) have been identified and are involved in the differentiation of the nervous system and other tissues. The EGF-like proteins Delta and Serrate act as ligands for Notch1. Mature Notch proteins are heterodimeric receptors formed by cleavage of precursor proteins into an extracellular subunit (NEC) and a transmembrane subunit (Ntm) containing the intracellular domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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