Thermo Fisher Scientific MED13 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human MED13 protein. Validated for IHC (Paraffin) with 1:50–1:100 dilution. Supplied as liquid, 1 mg/mL, purified by antigen affinity chromatography. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human MED13 (amino acids 681–730, UniProt ID: Q9UHV7-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635347 |
Product Specific Information
This antibody detects endogenous levels of total MED13 protein.
Target Information
The MED13 gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex required for the expression of most genes.
The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex.
MED13 is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator.
[Information provided by RefSeq]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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