Thermo Fisher Scientific MSRA Polyclonal Antibody
MSRA 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반, 액상 형태, 1 mg/mL 농도. 산화 손상 방어 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MSRA (Accession Q9UJ68), corresponding to amino acid residues V121–A171 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850127 |
Product Specific Information
This antibody detects endogenous levels of total MSRA.
Target Information
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to methionine (Met). The catalytic activity of MsrA depends on bound metal and cofactors and requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. Its substrates include calmodulin, HIV protease, and α1-proteinase inhibitor. Recent studies suggest a connection between MsrA and Alzheimer’s disease in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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