Thermo Fisher Scientific PRTFDC1 Polyclonal Antibody
PRTFDC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 면역침전(IP)에 적합하며, 액상 형태로 제공. 1 mg/mL 농도, 4°C 보관, 연구용으로만 사용 가능.
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Applications
Immunoprecipitation (IP)
- Tested Dilution: 8–15 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 175 to 225 of human Phosphoribosyltransferase domain-containing protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to hypoxanthine phosphoribosyltransferase (HPRT1) and may have originated from a gene duplication event of a common ancestor gene.
Recent studies show that CpG islands in the PRTFDC1 promoter can be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth, while knockdown promoted cell proliferation, suggesting that PRTFDC1 functions as a tumor suppressor gene.
At least three isoforms of PRTFDC1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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