Thermo Fisher Scientific cIAP2 Monoclonal Antibody (OTI3G4)
Western blot, ICC/IF, Flow cytometry에 사용 가능한 인간 반응성 cIAP2 단클론 항체. Mouse IgG1 아이소타입으로, E.coli에서 발현된 인간 BIRC3 단백질(aa 255–529)을 면역원으로 제작. 1 mg/mL 농도의 액상 항체로, -20°C에서 보관. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 255–529 of BIRC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724143 |
Target Information
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases. It inhibits apoptosis induced by serum deprivation but not apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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