Thermo Fisher Scientific Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Monoclonal Antibody (3D3)
Podocalyxin (PODXL) 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체. 인간, 토끼, 쥐 반응성. WB, IHC, Flow 등 다양한 응용 가능. 단백질 A/G로 정제된 액상 형태로 연구용 사용에 적합.
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Thermo Fisher Scientific Podocalyxin (PODXL) Monoclonal Antibody (3D3)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Immunoprecipitation (IP) | 1–2 µg/500 µg lysate |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D3 |
| Immunogen | Recombinant protein fragment containing intracellular, transmembrane, and part of extracellular domain of human podocalyxin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include:
- Binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements
- Playing a role in hematopoietic cell differentiation
- Being expressed in vascular endothelium cells and binding to L-selectin
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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