Thermo Fisher Scientific CCR7 Polyclonal Antibody
CCR7 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF 등에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 Liquid 형태, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CCR7 (Accession P32248), corresponding to amino acid residues S175–V225 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853569 |
Product Specific Information
Antibody detects endogenous levels of total CCR7.
Target Information
CCR7 is a member of the G protein coupled receptor family, a subfamily of chemokine receptors. It was identified as being induced by the Epstein Barr virus (EBV) and is thought to mediate EBV effects on B lymphocytes. CCR7 is expressed in blood, bone marrow, lymph node, and intestine, particularly in lymphoid tissues and activated B and T lymphocytes. It plays a role in controlling the migration of memory T cells to inflamed tissues and stimulates dendritic cell maturation. The chemokine ligand CCL19 (ECL) is a specific ligand for this receptor. Receptors in the C-C chemokine family, including CCR1–5 and the Duffy antigen, are important for T cell chemotaxis and phagocytic cell migration to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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