Thermo Fisher Scientific UHRF2 Monoclonal Antibody (OTI4G10), TrueMAB
UHRF2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human 시료에 반응하며, 1:500~1:2,000 희석 사용 권장. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 세포주기 조절 및 종양 발생 연구에 활용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–288 of human UHRF2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a nuclear protein involved in cell-cycle regulation. The encoded protein functions as a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), potentially contributing to tumorigenesis. It contains NIRF_N, PHD finger, SRA, and RING finger domains essential for cell proliferation regulation. The protein may also play a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants, some of which are non-protein coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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