Thermo Fisher Scientific Phospho-GluR4 (Ser862) Polyclonal Antibody
Phospho-GluR4 (Ser862) 폴리클로날 항체로, GluR4 단백질의 Ser862 인산화 부위를 특이적으로 인식합니다. Western blot 및 IHC(파라핀 절편)에 적합하며, 뇌 신경전달 연구에 유용합니다. Thermo Fisher Scientific에서 공급합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human GluR4 around the phosphorylation site of Ser862 (R-L-SP-I-T) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555095 |
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play important roles in neural plasticity, development, and neurodegeneration. Ionotropic glutamate receptors are classified into NMDA and kainate/AMPA receptors, both functioning as glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors, consisting of subunits GluR1–GluR7, are co-localized with NMDA receptors at many synapses and primarily mediate fast excitatory neurotransmission by glutamate. In contrast, NMDA receptors exhibit slower kinetics and higher Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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