Thermo Fisher Scientific AKAP4 Polyclonal Antibody
Human AKAP4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000–1:2,500 희석 범위로 검증됨. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 정자 운동 및 신호전달 연구에 적합한 연구용 항체.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AKAP4. Recombinant protein control fragment (Product #RP-92144). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637810 |
Product Specific Information
Immunogen sequence:
SALKLIQYHL TQQTKGKDTC EEDCPGSTMG YMAQSTQYEK CGGGQSAKAL SVKQLESHRA PGPSTCQKEN QHLDSQKMDM SNIVLMLIQK LLNENPFKCE DPCEGENKCS EPRASKAASM SNRSDKAEEQ CQEHQELDCT SGMKQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 69%
- Rat: 65%
Target Information
A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that bind to the regulatory subunit of protein kinase A (PKA) and localize the holoenzyme to specific cellular compartments.
AKAP4 (also known as hAKAP82) is a major sperm fibrous sheath protein distributed along the entire length of the human sperm flagellum.
It is implicated in sperm motility and regulation of signal transduction pathways and has been proposed as a potential biomarker for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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