Thermo Fisher Scientific DSC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DSC1. Recombinant protein control fragment (Product #RP-90225). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DSC1,uniProtId:Q08554-1,ncbiNodeId:9606,antigenRange:558-681,antigenLength:894,antigenImageFileName:PA5-53004_DSC1_Q08554-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53004_DSC1_Q08554-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640799

Product Specific Information

Immunogen sequence: SCTGTLVVHL DDYNDHAPQI DKEVTICQNN EDFAVLKPVD PDGPENGPPF QFFLDNSASK NWNIEEKDGK TAILRQRQNL DYNYYSVPIQ IKDRHGLVAT HMLTVRVCDC STPSECRMKD KSTR

Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 70%.

Target Information

The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.