Thermo Fisher Scientific TRAF6 Polyclonal Antibody
TRAF6 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. 인체 TRAF6 단백질(472–522 aa)을 면역원으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 472 and 522 of Human TNF Receptor-Associated Factor 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are adaptor proteins that link the TNF receptor superfamily to signaling pathways, playing key roles in regulating cell death and stress responses. TRAF proteins share homology regions enabling receptor and inter-TRAF interactions, activating diverse signaling cascades. For example, TRAF2 and TRAF3 bind CD40 to mediate NF-κB activation in B lymphocytes, while TRAF2 and TRAF6 are required for CD40 signaling in non-hematopoietic cells. TRAF2 also associates with LTβR, TRAF3, and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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