Thermo Fisher Scientific Phospho-SHP2 (Tyr542) Polyclonal Antibody
Human 및 Mouse에서 반응하는 Phospho-SHP2 (Tyr542) 폴리클로날 항체. Western blot 및 Immunocytochemistry에 사용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로, 세포 신호전달 연구에 적합. 동결건조 형태로 제공되며 PBS와 trehalose 용액에 재구성 가능.
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Thermo Fisher Scientific Phospho-SHP2 (Tyr542) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–10 µg/mL |
| Immunocytochemistry (ICC/IF) | 3–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphopeptide containing human SHP-2 Y542 site |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608103 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that mediate phospho-tyrosine binding and substrate interactions.
It is widely expressed in most tissues and plays a regulatory role in cell signaling events important for mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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